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https://www.sciencedirect.com/science/article/pii/B978032340232300128X
Acute liver failure (ALF) is a severe disease that can occur in healthy individuals. The current definition of ALF is acute liver injury associated with coagulopathy and altered mental status for less than 26 weeks with no prior history of liver disease.Author: Harvey S. Chen, Jian Yang, Scott L. Nyberg
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649611/
The fact that liver failure constitutes a life-threatening condition and can, in most cases, only be overcome by orthotopic liver transplantation, lead to the development of various artificial and bioartificial liver support devices. While artificial systems are based on the principles of adsorption ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265598/
Dec 14, 2014 · Core tip: In this study, the authors evaluated the safety, efficacy, and clinical feasibility of a hybrid bioartificial liver support system (HBALSS) with Chinese human liver cells for the treatment of acute liver failure in monkeys. The bioartificial liver significantly reduced serum biochemistry levels and extended animal survival time.Cited by: 10
https://en.wikipedia.org/wiki/Liver_support_systems
Liver support systems, such as MARS, are very important to stabilize patients with acute or acute on chronic liver failure and avoid organ dysfunction, as well as a bridge-to-transplant. Although initial in-hospital costs are high, they are worth for the favorable outcome.Specialty: hepatology
https://clinicaltrials.gov/ct2/show/NCT03084198
Mar 20, 2017 · Safety and Efficacy of hiHep Bioartificial Liver Support System to Treat Acute Liver Failure The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.
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