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https://www.researchgate.net/publication/5559536_Artificial_Liver_Support_Systems_in_the_Management_of_Complications_of_Cirrhosis
Artificial Liver Support Systems in the Management of Complications of Cirrhosis Article · Literature Review in Seminars in Liver Disease 28(1):96-109 · March 2008 with 29 Reads
https://en.wikipedia.org/wiki/Liver_support_systems
Liver support systems are therapeutic devices to assist in performing the functions of the liver in persons with liver damage.. The primary functions of the liver include removing toxic substances from the blood, manufacturing blood proteins, storing energy in the form of glycogen, and secreting bile.The hepatocytes that perform these tasks can be killed or impaired by disease, resulting in ...Specialty: hepatology
https://www.sciencedirect.com/science/article/pii/B9780123985231000239
In Suzhou, China, Gan et al. tested another Hybrid Artificial Liver Support System (HALSS) in 10 patients suffering severe liver failure . This system differs from HBAL in that it includes a hemo-adsorba column, to remove bilirubin and toxins and because the bioreactor is filled with spheroid porcine hepatocytes.Author: Xavier Wittebole, Diego Castanares-Zapatero, Christine Collienne, Olga Ciccarelli, Philippe Hantson,...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003263/
Apr 23, 2014 · Introduction. Cirrhosis represents the end stage of chronic liver disease that is accompanied by progressive fibrosis and is characterized by development of regenerative nodules and a sustained chronic inflammatory response.1 Once established, cirrhosis is irreversible, and is associated with increased morbidity, development of life-threatening complications, and decreased quality of life.Cited by: 26
https://link.springer.com/chapter/10.1007/978-3-319-13614-1_26
Apr 09, 2015 · This chapter describes currently available liver support systems, their operational characteristics, limitations, evidence of clinical efficacy, and prospects for future development. Keywords Bio-artificial liver devices End-stage liver disease Cirrhosis MARS system Acute liver failure Acute-on-chronic liver failure Hepatorenal syndrome ...Author: Mansoor Bangash, Banwari Agarwal, Rajiv Jalan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394109/
Apr 14, 2015 · Stadlbauer V, Davies NA, Sen S, Jalan R. Artificial liver support systems in the management of complications of cirrhosis. Semin Liver Dis. 2008; 28:96–109. 13. Kumar R, Krishnamoorthy TL, Tan HK, Lui HF, Chow WC. Change in model for end-stage liver disease score at two weeks, as an indicator of mortality or liver transplantation at 60 days ...Cited by: 9
https://link.springer.com/article/10.1007/s11011-008-9117-2
Bioartificial liver support systems use hepatocytes in an extracorporeal device connected to the patient’s circulation. Artificial liver support is intended to remove protein-bound toxins and water-soluble toxins without providing synthetic function. Both systems improve clinical and biochemical parameters and can be applied safely to patients.Cited by: 18
https://www.uptodate.com/contents/acute-liver-failure-in-adults-management-and-prognosis?search=liver%20failure&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1
INTRODUCTION. Acute liver failure refers to the development of severe acute liver injury with encephalopathy and impaired synthetic function (international normalized ratio [INR] of ≥1.5) in a patient without cirrhosis or preexisting liver disease [].While the time course that differentiates acute liver failure from chronic liver failure varies between reports, a commonly used cutoff is an ...
https://core.ac.uk/display/1749208
Artificial liver support systems in the management of complications of cirrhosis ... aims to describe the currently available artificial and bioartificial systems and reviews their effect on different complications of cirrhosis, such as liver function and hepatic hemodynamics, renal function and systemic hemodynamics, hepatic encephalopathy ...Author: V Stadibauer, NA Davies, S Sen and R Jalan
https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-018-0453-z
Nov 15, 2018 · Moreover, there is no precise recommendation on the effective timing of the initiation of artificial liver support systems. In this regard, the future prospects of artificial liver support systems should rely on the completion of adequately powered RCTs addressing these …Cited by: 3
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