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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356396/
The Bioartificial Liver Support System. The Bioartificial Liver Support System (BLSS) device, 80,81 developed in Pittsburgh, PA, uses 70 to 120 g of primary porcine hepatocytes. The hepatocytes, mixed with 20% collagen, are housed in an extrafiber space.Cited by: 268
https://www.ncbi.nlm.nih.gov/pubmed/15273544/
Clinical application of bioartificial liver support systems. van de Kerkhove MP(1), Hoekstra R, Chamuleau RA, van Gulik TM. Author information: (1)Department of Surgery (Surgical Laboratory), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.Cited by: 268
https://www.researchgate.net/publication/8435307_Clinical_Application_of_Bioartificial_Liver_Support_Systems
This manuscript reviews the significant clinical findings of ALF, as well as, the non-biologic liver support systems and the bioartificial liver devices that have been clinically tested to support ...
https://link.springer.com/chapter/10.1007/978-94-010-0159-5_38
Clinical application of bioartificial liver support systems ... Doll R, Gabelein G, Hohn W, Hofbauer R, Neuhaus P and Gerlach J. A method to assess biochemical activity of liver cells during clinical application of extracorporeal hybrid liver support. ... van Gulik T.M. (2003) Clinical application of bioartificial liver support systems. In ...Cited by: 268
http://journals.lww.com/annalsofsurgery/Abstract/2004/08000/Clinical_Application_of_Bioartificial_Liver.5.aspx
Among a variety of liver assist therapies, BAL therapy is marked as the most promising solution to bridge ALF patients to liver transplantation or to liver regeneration, because several BAL systems showed significant survival improvement in animal ALF studies. Until today, clinical application of 11 different BAL systems has been reported ...
https://insights.ovid.com/annals-surgery/ansu/2004/08/000/clinical-application-bioartificial-liver-support/5/00000658
Clinical Application of Bioartificial Liver Support Systems. ... Results: Eleven BAL systems found clinical application. Three systems were studied in a controlled trial, showing no significant survival benefits, in part due to the insufficient number of patients included. The other systems were studied in a phase I trial or during treatment of ...Cited by: 268
https://en.wikipedia.org/wiki/Liver_support_systems
Liver support systems are therapeutic devices to assist in performing the functions of the liver in persons with liver damage.. The primary functions of the liver include removing toxic substances from the blood, manufacturing blood proteins, storing energy in the form of glycogen, and secreting bile.The hepatocytes that perform these tasks can be killed or impaired by disease, resulting in ...Specialty: hepatology
https://www.researchgate.net/publication/7730178_Artificial_and_bioartificial_support_systems_for_liver_failure
Meta-analyses have been performed to evaluate beneficial and harmful effects of artificial and bioartificial support systems for acute and acute-on-chronic liver failure.
https://www.sciencedirect.com/topics/nursing-and-health-professions/bioartificial-liver
Bioartificial Liver Support. Bioartificial liver (BAL) systems rely on the use of hepatocytes (human or nonhuman) to perform detoxification and secretion of liver-synthesized factors. The selection of the ideal cell source and the design of more sophisticated bioreactors are the main issues in this field of research.
https://www.cirm.ca.gov/about-cirm/publications/clinical-translation-bioartificial-liver-support-systems-human-pluripotent
Home › About CIRM › Our Publications › Grantee publications › Clinical translation of bioartificial liver support systems with human pluripotent stem cell-derived hepatic cells. Clinical translation of bioartificial liver support systems with human pluripotent stem cell-derived hepatic cells. ... This mini-review paper introduced the ...
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