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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691094/
Dec 04, 2015 · Long-term inotropic therapy should be offered in selected patients. A detailed conversation with the patient and family shall be held, including a discussion on the risks and benefits of use of inotropes. Chronic heart failure patients awaiting heart transplants are candidates for intravenous inotropic support until the donor heart becomes ...Cited by: 30
https://healthjade.net/inotropic/
Dobutamine, the most commonly used inotropic agent worldwide, is a non-selective β1- and β2-adrenergic receptor agonist with variable activities on the α1 receptor 9). Prevalent β1- and β2-adrenergic receptor activation results in reduced afterload and increased stroke volume, heart rate and cardiac output at low doses.
https://www.uptodate.com/contents/inotropic-agents-in-heart-failure-with-reduced-ejection-fraction
May 25, 2018 · Those with HF with preserved ejection fraction (HFpEF; also known as diastolic HF) do not need inotropic support, and the myocardial effects of these agents may be detrimental in such patients. The efficacy of acute intravenous inotropic support is well established in patients with severe myocardial systolic dysfunction.
https://www.drugs.com/pro/dobutamine.html
Jun 29, 2005 · Dobutamine Injection, USP is indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of adults with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.
https://www.ahajournals.org/doi/abs/10.1161/circulationaha.107.728840
The pharmacology of dobutamine. Am J Med Sci. 1987; 294 ... Inotropic therapy for heart failure: an evidence-based approach. Am Heart J. 2001 ... Walker TL, Dutton D, Burgess D. Care processes and clinical outcomes of continuous outpatient support with inotropes (COSI) in patients with refractory endstage heart failure. J Card Fail ...Cited by: 323
https://bnf.nice.org.uk/drug/dobutamine.html
Dobutamine is a cardiac stimulant which acts on beta 1 receptors in cardiac muscle, and increases contractility. Indications and dose Inotropic support in infarction, cardiac surgery, cardiomyopathies, septic shock, cardiogenic shock, and during positive end expiratory pressure ventilation
https://www.drugs.com/drug-class/inotropic-agents.html
Inotropic agents are a group of medicines that affect the contraction of the heart muscle. Technically, inotropes can be divided into positive inotropes, which stimulate and increase the force of contraction of the heart muscle, and negative inotropes, which weaken the force of muscular contractions, decreasing how hard the heart has to work.
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