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https://pmj.bmj.com/content/75/883/269
May 01, 1999 · The use of dopamine for the prevention and treatment of acute renal failure is widespread. Its use is based on physiology suggesting selective renal vasodilation when it is infused at low dose. This article reviews the available data on the clinical use of dopamine. When used to prevent acute renal failure in high-risk treatments there is no evidence of benefit of dopamine …Cited by: 25
https://journals.lww.com/nursing/Fulltext/2004/09000/What_is__renal_dose__dopamine_.16.aspx
For years, renal dose dopamine has been used in critically ill patients with early signs of renal dysfunction. But recent studies question the drug's benefit because the positive inotropic and chronotropic effects can increase myocardial oxygen demand, leading to myocardial ischemia, especially in patients with heart disease.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728808/
Oct 11, 2012 · Alternatives to dopamine infusion exist, ... there were no differences in terms of mortality, need of renal replacement therapy, renal recovery, and peak serum creatinine among the patients. ... Weaver RA. “Renal support in critically ill patients: low-dose dopamine or low-dose dobutamine?” Crit Care Med. 1994 Dec; 22 (12):1919–25.
https://www.medscape.com/viewarticle/462075
Nov 09, 2019 · Dopamine is an inotropic agent that has vasodilatory effects at low doses. It is a common belief that low-dose dopamine may be helpful in the prevention and treatment of acute renal failure and is ...
https://www.movementdisorders.org/MDS-Files1/Education/Patient-Education/Infusion-Therapies/PatientLeaflet-InfusionTherapies-2017.pdf
Infusion therapies are treatments either through a small needle inserted under the skin or through a tube (catheter) inserted into your small intestine. These provide continuous flow of drugs throughout the day. Levodopa and apomorphine are two common infusion therapy drugs that address the lack of dopamine in the brain.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741438/
Jun 30, 2013 · A prospective, double-blind, randomized, controlled study concluded that low-dose dopamine can worsen renal perfusion in patients with acute renal failure, supporting a trend to abandon the routine use of low-dose dopamine in critically ill patients9). However, other studies challenge this conclusion.
https://www.uptodate.com/contents/renal-actions-of-dopamine
The renal actions of dopamine are discussed here. The use of dopamine in patients with shock is presented elsewhere. (See "Use of vasopressors and inotropes".) RENAL ACTIONS. Circulating and locally formed dopamine can affect both sodium excretion and renal hemodynamics via activation of the D1-like and D2-like receptors .
https://www.drugs.com/pro/dopamine-injection.html
Apr 11, 2018 · Begin infusion of diluted solution at doses of 2 – 5 mcg/kg/min of dopamine hydrochloride in patients who are likely to respond to modest increments of heart force and renal perfusion. In more seriously ill patients, begin infusion of diluted solution at doses of 5 mcg/kg/min of dopamine hydrochloride and increase gradually using 5 to 10 mcg/kg/min …1/10
https://globalrph.com/drugs/vasopressors-and-inotropes/
Used to support BP, CO and renal perfusion in shock. IMPORTANT NOTE: Renal shutdown may occur at doses greater than 50 micrograms/kilogram/minute. The infusion rate should be reduced if urine flow decreases without adequate peripheral effects. Administer into large vein to prevent the possibility of extravasation (central line administration).
https://reference.medscape.com/drug/intropin-dopamine-342435
Treatment of hypotension, low cardiac output, poor perfusion of vital organs; used to increase mean arterial pressure in septic shock patients who remain hypotensive after adequate volume expansion. 1-5 mcg/kg/min IV (low dose): May increase urine output and renal blood flow
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