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https://www.uptodate.com/contents/use-of-vasopressors-and-inotropes
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https://globalrph.com/drugs/vasopressors-and-inotropes/
Cardiac life support (initial): 2 to 5 mcg/kg/min - titrated to effect. Infusion may be increased by 1-4 mcg/kg/minute at 10 to 30 minute intervals until optimal response is obtained. If dosages >20-30 mcg/kg/minute are needed, a more direct-acting pressor may be …
https://healthfully.com/336497-how-dopamine-increases-blood-pressure.html
Aug 14, 2017 · Dopamine is a precursor to other catecholamine neurotransmitters, namely norepinephrine and epinephrine, or adrenalin. Catecholamines are generally “excitatory” in nature, meaning they increase your heart rate and cause your blood vessels to constrict, both of which lead to a rise in blood pressure.
https://www.thecardiologyadvisor.com/home/decision-support-in-medicine/cardiology/interventional-pharmacology-inotropes-and-vasopressors/
Dopamine. Dopamine is a naturally occurring neurotransmitter and the precursor of norepinephrine. Dopamine acts on several different receptors, each with different affinities for the drug: At low doses (2 to 5 µg/kg/min), stimulation of dopaminergic receptors leads to vasodilation in the renal, mesenteric, coronary, and cerebral beds.
https://www.drugs.com/drug-class/vasopressors.html
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 3 Jan 2020), Cerner Multum™ (updated 6 Jan 2020), Wolters Kluwer™ …
https://www.aliem.com/choosing-the-right-vasopressor-agent-in-hypotension/
Aug 20, 2013 · 5. When choosing between similar agents, does evidence support use of a specific agent over another? The majority of evidence comparing pressors head-to-head has been done in patients with septic shock; the largest amount of data has compared high-dose dopamine to norephinephrine.
http://www.surgicalcriticalcare.net/Guidelines/Vasopressors%20and%20Inotropes%20in%20Shock.pdf
support a Level I recommendation. ... dopamine and norepinephrine can cause increased myocardial oxygen demand and may aggravate ischemia. This can lead to arrhythmias making it important to titrate to the lowest dose needed to improve tissue perfusion. For patients who are in a low output cardiogenic shock dobutamine may be
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413841/
Despite widespread use, the evidence base for the use of inotropes and vasopressors in critically ill patients is limited. Clearly, many patients would not survive without inotropic support, but there is, nonetheless, considerable variation in clinical practice.Cited by: 115
http://nicuvet.com/nicuvet/Equine-Perinatoloy/NICU%20Lectures/Inotropes%20and%20Pressors.htm
Dopamine has dopaminergic activity at low doses, b 1 & b 2 activity at moderate doses, and a 1 activity at high doses. It causes norepinephrine release from nerve terminals which has lead to the suggestion that this is its major mode of action at high doses and the suggested limitation in critical patients who become depleted.
https://ccme.osu.edu/ConferenceBrochure/1365-Cardiogenic%20Shock%20and%20Aortic%20Stenosis%202013.pdf
Cardiogenic Shock + Critical Aortic Stenosis = Run the Other Way?!!! Ernest L. Mazzaferri Jr, MD, FACC ... BP 70/40 on 20 mcg/min dopamine, hypoperfusing TAVR Consult Team called for Stat Consult Case Study . 5 Palliative ... Hypotension requiring inotropic or pressor support or MAP < 60 mmHg ...
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