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http://www.vhersey.com/2017/07/17/jumbo-frames-make-sure-it-is-setup-end-to-end/
Jumbo Frames must be configured correctly end-to-end. This means on the vSwitch, vmkernel interfaces, physical switches, endpoint – everything must be configured to support the larger frames end-to-end. Using larger frames will provide more efficient processing of network traffic (in many cases) but it does require a bit more complexity.
https://www.cisco.com/c/en/us/support/docs/servers-unified-computing/ucs-b-series-blade-servers/117601-configure-UCS-00.html
Apr 09, 2014 · If jumbo frames are used, you must ensure that the UCS and storage target, as well as all of the network equipment between, are able and configured in order to support the larger frame size. This means that the jumbo MTU must be configured end-to-end (initiator to target) in order for it to be effective across the domain.
https://docs.vmware.com/en/VMware-vSphere/6.5/com.vmware.vsphere.networking.doc/GUID-53F968D9-2F91-41DA-B7B2-48394D997F2A.html
Jumbo frames let ESXi hosts send larger frames out onto the physical network. The network must support jumbo frames end-to-end that includes physical network adapters, physical switches, and storage devices. Before enabling jumbo frames, check with your hardware vendor to ensure that your physical network adapter supports jumbo frames.
https://communities.vmware.com/thread/433467
Jan 28, 2013 · Re: Jumbo Frames End to End Linjo Jan 28, 2013 4:08 AM ( in response to RanjnaAggarwal ) If the "do-not-fragment" flag is set on the packet it will simply be dropped by the network device that is not configured for Jumbo Frames.
https://www.networkworld.com/article/2224722/jumbo-frames.html
The key concept to keep in mind is that all the network devices along the communication path must support jumbo frames. Jumbo frames needs to be configured to work on the ingress and egress interface of each device along the end-to-end transmission path.
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