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https://www.drugs.com/drug-class/inotropic-agents.html
Inotropic agents are a group of medicines that affect the contraction of the heart muscle. Technically, inotropes can be divided into positive inotropes, which stimulate and increase the force of contraction of the heart muscle, and negative inotropes, which weaken the force of muscular contractions, decreasing how hard the heart has to work.
https://www.texasheart.org/heart-health/heart-information-center/topics/inotropic-agents/
Inotropic agents, or inotropes, are medicines that change the force of your heart's contractions. Positive inotropes strengthen the force of the heartbeat. Negative inotropes weaken the force of the heartbeat. Both kinds are used in the treatment of many different cardiovascular conditions.
https://www.pharmaceutical-journal.com/learning/learning-article/use-of-inotropes-in-critical-care/11049283.fullarticle
It is sometimes used for bradycardic patients requiring inotropic support. Noradrenaline. Because noradrenaline acts primarily via a 1 receptors, it is usually used as a vasopressor (increasing SVR to maintain MAP) rather than an inotrope. It is often used with other inotropes, such as dobutamine, to maintain adequate perfusion, as discussed ...
https://optioncare.com/home-infusion-inotropic-therapy-helps-heart-failure-patients-enjoy-better-quality-life-option-care-research-shows/
Jul 12, 2017 · Option Care’s signature Home Infusion Plus services include the clinical management of infusion medicines, nursing support and care coordination. Option Care’s multidisciplinary team of more than 1,800 clinicians – including pharmacists, nurses and dietitians – are able to provide home infusion service coverage for nearly all patients ...
https://healthjade.net/inotropic/
Positive inotropic drugs are used to treat congestive heart failure and heart rhythm problems (atrial arrhythmias). Positive inotropic drugs can increase blood flow throughout your body and reduce swelling in your hands and ankles. Positive inotropic agents used for …
https://www.thecardiologyadvisor.com/home/decision-support-in-medicine/cardiology/interventional-pharmacology-inotropes-and-vasopressors/
In the presence of severe hypotension, beta-2 induced peripheral vasodilation may be harmful and the addition of vasoconstrictors, such as dopamine or norepinephrine, may be necessary to support the blood pressure. Phosphodiesterase inhibitors. The hemodynamic actions of milrinone result from a combination of inotropic and vasodilating properties.
http://www.surgicalcriticalcare.net/Guidelines/Vasopressors%20and%20Inotropes%20in%20Shock.pdf
support a Level I recommendation. ... has traditionally been the drug of choice, owing to its vasopressor and inotropic activity. Norepinephrine was preferred over dopamine in patients with more severe hypotension due to its more potent vasoconstriction. However, recent literature showing a potential increase in mortality with dopamine over
https://www.uptodate.com/contents/inotropic-agents-in-heart-failure-with-reduced-ejection-fraction
May 25, 2018 · The efficacy of acute intravenous inotropic support is well established in patients with severe myocardial systolic dysfunction. However, the efficacy of chronic administration of oral inotropic agents other than digoxin in ambulatory patients with HF remains unproven.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413841/
Despite widespread use, the evidence base for the use of inotropes and vasopressors in critically ill patients is limited. Clearly, many patients would not survive without inotropic support, but there is, nonetheless, considerable variation in clinical practice.Cited by: 115
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