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https://www.nature.com/articles/nrn2797
Mar 10, 2010 · This glial support of axonal integrity may be relevant for a number of neurological and psychiatric diseases. ... I propose that ensheathing glia provide trophic support to axons that are ...Cited by: 456
https://dev.biologists.org/content/128/2/207
Trophic support and cell-cell contact restrict glial movement and axonal trajectories. The significance of this relationship is revealed when neuron-glia interactions are disrupted by neuronal ablation or mutation in the glial cells missing gene, which eliminates glia, when axons and glia cross the midline despite continued midline repellent ...Cited by: 87
https://ocw.mit.edu/courses/biology/7-343-neuron-glial-cell-interactions-in-biology-and-disease-spring-2007/syllabus/
Syllabus Readings ... Since then, glial cells have been regarded as passive nervous system components that provide insulation and tropic support for neurons. This view has been challenged in the last few years, and we now know that glial cells actively control synapse formation, synapse function and …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241182/
Amyotrophic Lateral Sclerosis is a motor neuron disease affecting upper and lower motor neurons in motor cortex, brain stem and spinal cord. ... which surround motor neurons and provide nutritional and trophic support to them. The study of glial cells in the past has led to the conclusion that ALS is a non-cell autonomous multifactorial disease ...Cited by: 141
https://quizlet.com/209613829/plate-4-2-glial-cells-flash-cards/
glial cells of the PNS, they surround all axons, myelinating many of them, and provide trophic support, facilitate regrowth of PNS axons, and clean away cellular debris. Clinical Note:
https://www.ncbi.nlm.nih.gov/pubmed/20216548
Here, I propose that ensheathing glia provide trophic support to axons that are metabolically isolated, and that myelin itself might cause such isolation. This glial support of axonal integrity may be relevant for a number of neurological and psychiatric diseases. PMID: 20216548 [Indexed for MEDLINE] Publication Types: Research Support, Non-U.S ...Cited by: 456
https://www.sciencedirect.com/science/article/pii/S0166223605003073
Trophic support of glia by neurons. Glia become intimately associated with axons during development, and the ultimate survival of many glial cell types depends on trophic factors supplied by the neurons they ensheath. Such a mechanism enables proper balancing of neuronal and glial populations in the developing nervous system.Cited by: 216
https://www.sciencedirect.com/topics/medicine-and-dentistry/trophic-factor
The glial cell line-derived neurotrophic factor (GDNF) is of particular interest in PD treatment since the landmark observation demonstrated that GDNF could support the viability of midbrain dopaminergic neurons in tissue culture (Lin et al., 1993a) and several in vivo studies confirmed the ability of GDNF to prevent degeneration of ...
https://quizlet.com/130344052/glial-cells-flash-cards/
Start studying Glial Cells. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Search. ... Glial metabolic support. ... Release of GDNF provides trophic support for midbrain DA neurons and supports growth of spinal cord motoneurons …
https://en.wikipedia.org/wiki/Oligodendrocyte
Metabolic support. Oligodendrocytes interact closely with nerve cells and provide trophic support by the production of glial cell line-derived neurotrophic factor (GDNF), brain-derived neurotrophic factor (BDNF), or insulin-like growth factor-1 (IGF-1).Location: Central nervous system
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