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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649611/
The fact that liver failure constitutes a life-threatening condition and can, in most cases, only be overcome by orthotopic liver transplantation, lead to the development of various artificial and bioartificial liver support devices. While artificial systems are based on the principles of adsorption ...
https://www.sciencedirect.com/topics/medicine-and-dentistry/liver-support
Liver Support Devices (Albumin Dialysis) Liver support devices (LSDs) were developed to support liver function in the context of fulminant hepatic failure or cirrhosis. These devices theoretically remove albumin-bound toxins and xenobiotics better than the more …
https://www.ncbi.nlm.nih.gov/pubmed/11385970/
Artificial liver-support devices attempt to bridge patients with fulminant hepatic failure until either a suitable liver allograft is obtained for transplantation or the patient's own liver regenerates sufficiently to resume normal function. It is thought that toxins contribute to the clinical picture of fulminant hepatic …Cited by: 58
https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/10.1002/lt.24396
liver support devices (ELSDs) is the idea that if the patient’s liver and extrahepatic organs can be sup-ported long enough, recovery should be possible because of the regeneration potential of the liver.(2) Alternative aims of ELSD may be to “bridge” liver failure patients to liver transplantation or to supportCited by: 14
https://journals.lww.com/co-criticalcare/Abstract/2008/04000/Liver_support_devices.15.aspx
Many liver support devices exist and are discussed. Clinical data on artificial devices are rapidly emerging, especially on the molecular adsorbents recirculating system, and fractionated plasma separation and adsorption (Prometheus). While hepatic encephalopathy is improved by the molecular adsorbents recirculating system and probably Prometheus too, neither system has been shown to …
https://aasldpubs.onlinelibrary.wiley.com/doi/full/10.1002/lt.24396
Jan 19, 2016 · Mortality in patients with liver failure who cannot be rescued with liver transplantation remains high despite improvements in supportive care. 1 The fundamental thinking behind the use of extracorporeal liver support devices (ELSDs) is the idea that if the patient's liver and extrahepatic organs can be supported long enough, recovery should be ...Cited by: 14
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