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https://www.thecardiologyadvisor.com/home/decision-support-in-medicine/cardiology/interventional-pharmacology-inotropes-and-vasopressors/
General (including evidence of efficacy) Inotropes and vasopressors Inotropes and/or vasopressors are essential in the management of cardiogenic shock complicating myocardial infarction/ischemia and in the treatment of hemodynamic instability occurring during coronary interventions. They help stabilize patients at risk for progressive hemodynamic collapse or serve as a life-sustaining bridge ...
https://www.ahajournals.org/doi/abs/10.1161/circulationaha.107.728840
Inotropes and Vasopressors. Review of Physiology and Clinical Use in Cardiovascular Disease ... Inotropic therapy for heart failure: an evidence-based approach. Am ... Walker TL, Dutton D, Burgess D. Care processes and clinical outcomes of continuous outpatient support with inotropes (COSI) in patients with refractory endstage heart failure ...Cited by: 323
https://neoreviews.aappublications.org/content/16/6/e351?sso_redirect_count=5&nftoken=00000000-0000-0000-0000-000000000000&nftoken=00000000-0000-0000-0000-000000000000
Jun 01, 2015 · Hemodynamic instability is a common problem in neonates and has important implications for long-term outcomes. Inotropes and vasopressors are commonly used to treat low blood pressure or poor perfusion in neonatal intensive care, despite limited evidence to guide optimal management in specific clinical situations. Dopamine is the most commonly used agent in clinical practice, increasing …Cited by: 3
https://www.ncbi.nlm.nih.gov/books/NBK385327/
Sepsis management consists of a bundle of actions to be taken as soon as possible after diagnosis. Inotropic agents, which alter heart muscle contractions, and vasopressors, which cause the constriction of blood vessels, are important parts of sepsis treatment. Some agents have characteristics of both.
http://www.surgicalcriticalcare.net/Guidelines/Vasopressors%20and%20Inotropes%20in%20Shock.pdf
Vasopressors should be initiated in refractory hypotension despite adequate fluid and/or blood product resuscitation. In low cardiac output states, the use of an inotropic agent should be considered. RECOMMENDATIONS All shock states • Level 1 Vasopressors should only be initiated with/after adequate resuscitation is provided
https://www.pharmaceutical-journal.com/learning/learning-article/use-of-inotropes-in-critical-care/11049283.fullarticle
It is sometimes used for bradycardic patients requiring inotropic support. Noradrenaline. Because noradrenaline acts primarily via a 1 receptors, it is usually used as a vasopressor (increasing SVR to maintain MAP) rather than an inotrope. It is often used with other inotropes, such as dobutamine, to maintain adequate perfusion, as discussed ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495871/
This review assesses available evidence for the use of specific vasopressors in the management of septic shock. Use of adjunctive vasopressor therapy is also evaluated, examining the potential value of individual agents. Lastly, inotropic agents are evaluated for use in patients with myocardial dysfunction.Cited by: 4
https://www.uptodate.com/contents/use-of-vasopressors-and-inotropes
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https://www.drugs.com/drug-class/inotropic-agents.html
Inotropic agents are a group of medicines that affect the contraction of the heart muscle. Technically, inotropes can be divided into positive inotropes, which stimulate and increase the force of contraction of the heart muscle, and negative inotropes, which weaken the force of muscular contractions, decreasing how hard the heart has to work.
https://en.wikipedia.org/wiki/Inotrope
An inotrope is an agent that alters the force or energy of muscular contractions.Negatively inotropic agents weaken the force of muscular contractions. Positively inotropic agents increase the strength of muscular contraction. The term inotropic state is most commonly used in reference to various drugs that affect the strength of contraction of heart muscle (myocardial contractility).
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