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https://www.sciencedirect.com/topics/veterinary-science-and-veterinary-medicine/liver-support-systems
Artificial liver support systems can work as a bridge for patients with severe liver disease, either to give them time to recover or to go to transplant. Many attempts have been made to develop artificial liver support devices (ALSD).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356396/
The most promising nonbiologic support therapies combine detoxification of water-soluble and protein-bound toxins in a dialysis system, such as the Molecular Adsorbents Recirculating System (MARS), 29–32 the albumin dialysis system, 33 the Artificial Liver Support System (ALSS), 34 and PF-Liver …Cited by: 268
https://read.qxmd.com/read/17464150/liver-support-systems
Systems supporting liver function may be useful to avoid further complications due to the typical toxic state, 'bridging' the patients to the transplantation, or, in the event of an acute decompensation of a chronic liver disease, sustain liver function long enough to permit the organ's regeneration and functional recovery.
https://link.springer.com/chapter/10.1007/978-3-319-13614-1_26
Apr 09, 2015 · Bio-artificial devices aim to replace the whole gamut of liver functions (synthesis, biotransformation, detoxification, and excretion) through the use of cultured hepatocytes, whereas artificial devices predominantly employ blood purification and detoxification strategy through processes targeting albumin-based dialysis and the use of adsorbents.Author: Mansoor Bangash, Banwari Agarwal, Rajiv Jalan
https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-018-0453-z
Nov 15, 2018 · Some of the substances removed by the different artificial hepatic support systems include conjugate or unconjugated bilirubin or protoporphyrin, bile acids, glycoside derivatives, phenols, short- and medium-chain fatty acids, such as octanoate, or heterocyclic organic compounds.Cited by: 3
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