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https://miami.pure.elsevier.com/en/publications/mechanical-ventilatory-support-in-preterm-infants
A large proportion of premature infants presents with acute respiratory failure after birth and require mechanical ventilatory support. In addition to conventional mechanical ventilation, an increasing number of these infants are currently supported by newer modes including synchronized, volume targeted and noninvasive mechanical ventilation.Cited by: 8
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883206/
Despite surfactant and mechanical ventilation being the standard of care for preterm infants with respiratory failure, non-invasive respiratory support is increasingly being employed in neonatal units.
https://www.verywellfamily.com/respiratory-support-in-the-nicu-2748423
Nov 24, 2019 · Mechanical ventilation is used for premature babies who are too weak to breathe on their own. The ventilator provides a mixture of oxygen and air which is pumped through a tube into the windpipe and then drawn out, replicating the natural pattern of breathing.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109382/
Preterm infants requiring mechanical ventilation showed a higher risk of death and bronchopulmonary dysplasia. After controlling for gestational age, antenatal corticosteroid use, maternal preeclampsia and chorioamnionitis, the survival rate without bronchopulmonary dysplasia remained significantly lower in the mechanically ventilated group.Cited by: 15
https://www.sciencedirect.com/science/article/pii/S1875957219305236
Oct 11, 2019 · Mechanical ventilation (MV) causes lung injury through different mechanisms including volutrauma, barotrauma, rheotrauma, atelectotrauma and biotrauma. 1 The resulting ventilator induced lung injury is the major cause of bronchopulmonary dysplasia (BPD), 2 which can lead to multiple respiratory problems in infancy and thereafter. 3 Consequently, as a possible means to prevent lung injury and BPD, non-invasive ventilation …Author: Ammar M.H. Shehadeh
https://www.researchgate.net/publication/230809734_Weaning_Infants_from_Mechanical_Ventilation
Despite a even more frequent use to non-invasive respiratory support, mechanical ventilation is stilloften necessary for supporting premature infants with lung disease.
https://pediatrics.aappublications.org/content/133/1/171
Emerging evidence indicates that early CPAP is an effective strategy for respiratory support in extremely preterm infants, including very immature infants. CPAP appears to be at least as safe and effective as early surfactant therapy with mechanical ventilation. 9
https://www.intechopen.com/books/respiratory-management-of-newborns/mechanical-ventilation-of-the-infant-with-severe-bronchopulmonary-dysplasia
Bronchopulmonary dysplasia (BPD) was first characterized by Northway and colleagues in 1967 as a chronic lung disease afflicting premature infants after neonatal intensive care unit (NICU) treatment that included administration of oxygen and mechanical ventilation . Early descriptions of BPD noted profound airway inflammation, fibrosis, areas of emphysema, and a heterogeneous physiology.Author: Edward G. Shepherd, Susan K. Lynch, Daniel T. Malleske, Leif D. Nelin
https://www.uptodate.com/contents/mechanical-ventilation-in-neonates#!
Jun 29, 2018 · Along with other technologic advancements, such as the administration of antepartum corticosteroids and replacement surfactant therapy, mechanical ventilation has led to improved neonatal survival, especially for preterm infants born less than 30 weeks gestation with immature lung function.
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