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https://www.ncbi.nlm.nih.gov/pubmed/21068833
Nov 11, 2010 · Glial cells that myelinate axons were found to have a dual role by also supporting the long-term integrity of those axons. This function may be independent of myelin itself. Myelin abnormalities cause a number of neurological diseases, and may also contribute to complex neuropsychiatric disorders.Cited by: 751
https://www.nature.com/articles/nature09614
Nov 10, 2010 · Glial cells that myelinate axons were found to have a dual role by also supporting the long-term integrity of those axons. This function may be independent of myelin itself.Cited by: 751
https://www.researchgate.net/publication/47743038_Myelination_and_support_of_axon_integrity_by_glia
Cell biology and mouse genetics have provided insight into axon-glia signalling and the molecular architecture of the myelin sheath. Glial cells that myelinate axons were found to have a dual role by also supporting the long-term integrity of those axons.Author: Klaus-Armin Nave
http://www.jneurosci.org/content/31/49/18185
Dec 07, 2011 · Axon–glial integrity is disrupted, whereas myelin and axonal integrity remains intact. A, Disruption of axon–glial integrity was defined as reduced and discontinuous granular accumulation of the MAG staining in response to hypoperfusion compared with shams. In contrast, the integrity of the myelin sheath (assessed by MBP) and integrity of ...
https://www.deepdyve.com/lp/nature-publishing-group-npg/myelination-and-support-of-axonal-integrity-by-glia-YQa2HqBdNw
Nov 10, 2010 · Myelination and support of axonal integrity by glia Cell biology and mouse genetics have provided insight into axon–glia signalling and the molecular architecture of the myelin sheath. Glial cells that myelinate axons were found to have a dual role by also supporting the long-term integrity of those axons.
https://cshperspectives.cshlp.org/content/8/1/a020479.full
Jun 22, 2015 · Myelination is a complex sequence of events that is best understood when conceptualized as separate steps, including (1) proliferation and migration of oligodendrocyte precursor cells (OPCs) in white matter tracts, (2) recognition of target axons and axon–glia signaling, (3) differentiation of OPCs into myelinating oligodendrocytes, (4) membrane outgrowth and axonal wrapping, (5) trafficking of membrane components, (6) myelin …Cited by: 198
https://www.annualreviews.org/doi/abs/10.1146/annurev.neuro.30.051606.094309
Jul 21, 2008 · Oligodendrocytes and Schwann cells are highly specialized glial cells that wrap axons with a multilayered myelin membrane for rapid impulse conduction. Investigators have recently identified axonal signals that recruit myelin-forming Schwann cells from an alternate fate of simple axonal engulfment.Cited by: 591
https://www.semanticscholar.org/paper/Myelination-and-the-trophic-support-of-long-axons-Nave/a1d4617d20d531d6518a521c5f5c222c6fe00e4b/figure/2
The encapsulated axon is proposed to reside in a milieu conditioned by the glia that can thereby support axonal energy metabolism. Non-compacted myelin defines a channel system (shown in dark blue) that is continuous with the glial cytoplasm and brings cellular metabolites close to the periaxonal space (shown in yellow).
https://www.ncbi.nlm.nih.gov/pubmed/21068833
Nov 11, 2010 · Glial cells that myelinate axons were found to have a dual role by also supporting the long-term integrity of those axons. This function may be independent of myelin itself. Myelin abnormalities cause a number of neurological diseases, and may also contribute to complex neuropsychiatric disorders.Cited by: 756
https://www.nature.com/articles/nature09614
Nov 10, 2010 · Glial cells that myelinate axons were found to have a dual role by also supporting the long-term integrity of those axons. This function may be independent of myelin itself.Cited by: 756
https://www.researchgate.net/publication/47743038_Myelination_and_support_of_axon_integrity_by_glia
Cell biology and mouse genetics have provided insight into axon-glia signalling and the molecular architecture of the myelin sheath. Glial cells that myelinate axons were found to have a dual role by also supporting the long-term integrity of those axons.Author: Klaus-Armin Nave
http://www.jneurosci.org/content/31/49/18185
Dec 07, 2011 · Axon–glial integrity is disrupted, whereas myelin and axonal integrity remains intact. A, Disruption of axon–glial integrity was defined as reduced and discontinuous granular accumulation of the MAG staining in response to hypoperfusion compared with shams. In contrast, the integrity of the myelin sheath (assessed by MBP) and integrity of ...
https://cshperspectives.cshlp.org/content/8/1/a020479.full
Jun 22, 2015 · Myelination is a complex sequence of events that is best understood when conceptualized as separate steps, including (1) proliferation and migration of oligodendrocyte precursor cells (OPCs) in white matter tracts, (2) recognition of target axons and axon–glia signaling, (3) differentiation of OPCs into myelinating oligodendrocytes, (4) membrane outgrowth and axonal wrapping, (5) trafficking of membrane components, (6) myelin …Cited by: 200
https://www.deepdyve.com/lp/nature-publishing-group-npg/myelination-and-support-of-axonal-integrity-by-glia-YQa2HqBdNw
Nov 10, 2010 · Myelination and support of axonal integrity by glia Cell biology and mouse genetics have provided insight into axon–glia signalling and the molecular architecture of the myelin sheath. Glial cells that myelinate axons were found to have a dual role by also supporting the long-term integrity of those axons.
https://www.annualreviews.org/doi/abs/10.1146/annurev.neuro.30.051606.094309
Jul 21, 2008 · Oligodendrocytes and Schwann cells are highly specialized glial cells that wrap axons with a multilayered myelin membrane for rapid impulse conduction. Investigators have recently identified axonal signals that recruit myelin-forming Schwann cells from an alternate fate of simple axonal engulfment.Cited by: 597
https://www.semanticscholar.org/paper/Myelination-and-the-trophic-support-of-long-axons-Nave/a1d4617d20d531d6518a521c5f5c222c6fe00e4b/figure/2
The encapsulated axon is proposed to reside in a milieu conditioned by the glia that can thereby support axonal energy metabolism. Non-compacted myelin defines a channel system (shown in dark blue) that is continuous with the glial cytoplasm and brings cellular metabolites close to the periaxonal space (shown in yellow).
https://ui.adsabs.harvard.edu/abs/2012Natur.485..517F
Oligodendrocytes, the myelin-forming glial cells of the central nervous system, maintain long-term axonal integrity. However, the underlying support mechanisms are not understood.Cited by: 781
https://www.sciencedirect.com/science/article/pii/S095943881730168X
Myelinating glial cells are well-known to insulate axons and to speed up action potential propagation. Through adjustments in the axonal coverage with myelin, myelin sheath thickness and possibly nodal/internode length oligodendrocytes are involved in fine …Cited by: 33
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