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https://www.researchgate.net/publication/26790667_Neurotrophic_Support_of_Midbrain_Dopaminergic_Neurons
Request PDF on ResearchGate Neurotrophic Support of Midbrain Dopaminergic Neurons In this chapter we review work on neurotrophic factors for midbrain dopaminergic neurons mainly from the …
https://www.ncbi.nlm.nih.gov/pubmed/19731552
Neurotrophic support of midbrain dopaminergic neurons. von Bohlen und Halbach O(1), Unsicker K. Author information: (1)Interdisciplinary Center for Neurosciences, Neuroanatomy, University of Heidelberg, Im Neuenheimer Feld 307 D-69120 Heidelberg, Germany. [email protected] by: 11
https://link.springer.com/chapter/10.1007%2F978-1-4419-0322-8_7
In this chapter we review work on neurotrophic factors for midbrain dopaminergic neurons mainly from the past decade, with a focus on neurotrophins and fibroblast growth factors. We summarize data...Cited by: 11
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187939/
In this context, glial cell line-derived neurotrophic factor (GDNF) and neurotrophin-4/5 (NT-4/5) support the improved growth and survival of DAergic neurons. Neurotrophic signaling pathways may be involved in these observed cell-surviving effects.
https://www.jneurosci.org/content/33/8/3363
Feb 20, 2013 · Here we report that brain-derived neurotrophic factor and neurotrophin-3 are anterogradely transported from midbrain dopaminergic neurons and support the survival of immature MSNs of the indirect and direct pathways, respectively, in the developing mouse striatum and LGE.Cited by: 16
https://www.sciencedirect.com/science/article/pii/S1043661818310247
Here, the present study investigated whether NAR promoted astroglial neurotrophic effects to support neurons and the underlying mechanisms as well. In primary rat midbrain neuron-glia co-cultures, NAR conferred neurotrophic effects to support dopaminergic (DA) neurons survival in the concentration- and time-dependent manners.Cited by: 5
https://www.jneurosci.org/content/26/43/11230
Oct 25, 2006 · A detailed morphometric and biochemical analysis including dopaminergic neuron number and size in SNC and VTA, and fiber density in the striatum and nucleus accumbens, and dopamine levels indicate that RET is not required for providing global trophic support to midbrain dopaminergic neurons in …Cited by: 125
https://www.pnas.org/content/106/7/2429
Feb 17, 2009 · Importantly, there is also evidence for neurotrophic support from glia (14, 15). However, the proteins underlying the neurotrophic support in Drosophila have remained elusive. The mammalian mesencephalic astrocyte-derived neurotrophic factor (MANF, also known as Armet) selectively promotes the survival of DA neurons in vitro .Cited by: 135
http://www.nature.com/articles/nature05957
Jul 05, 2007 · Importantly, CDNF induced behavioural recovery and restored the function of midbrain dopaminergic neurons in vivo as efficiently as GDNF. The exact …Cited by: 384
https://www.sciencedirect.com/science/article/pii/S0014579315009771
The neurotransmitter dopamine is produced by dopaminergic (DA) neurons and modulates diverse functions in the brain and throughout the body, including movement, memory, motivation and emotions , .The cell bodies of DA neurons are grouped in the ventral midbrain in the substantia nigra (SN), the ventral tegmental area (VTA) and the retro-rubal field (RRF).Cited by: 56
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