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https://academic.oup.com/molehr/article/15/12/843/1049045
Towards achieving these goals, more effective controlled ovarian stimulation regimes might be reverse engineered from the natural follicular life cycle. To which end, I posit three tactics for manipulating the ovarian paracrine system. Tactic 1: follicular priming with LH or hCGCited by: 31
https://www.ncbi.nlm.nih.gov/pubmed/19825856
Paracrine support of ovarian stimulation. Hillier SG(1). Author information: (1)Centre for Reproductive Biology, University of Edinburgh College of Medicine and Veterinary Medicine, Chancellor's Building, 47 Little France Crescent, Edinburgh EH16 4TJ, UK. [email protected] by: 31
https://www.researchgate.net/publication/26891468_Paracrine_support_of_ovarian_stimulation
During ovarian stimulation, increasing attention needs to be paid to the paracrine environment as more is learnt about the impact of these factors on steroidogenesis and cell growth and apoptosis.
http://europepmc.org/abstract/MED/19825856
Jan 01, 2010 · It is concluded that whereas there can be no one-size-fits-all approach to ovarian stimulation, treatment regimes based on paracrine principles and tailored to personal needs will always be more likely to achieve the desired outcome.Cited by: 31
https://www.sciencedirect.com/topics/medicine-and-dentistry/paracrine-stimulation
Ovarian cancers can express up to 1000 times more TNF-α than normal ovarian epithelial cells. Some 80% of ovarian cancers express TNF-α, regulated translationally and transcriptionally through NF-κB. Ovarian cancer cells can also express both TNFRI and TNFRII, receptors that permit both autocrine and paracrine stimulation.
https://en.wikipedia.org/wiki/Paracrine
Paracrine signaling is a form of cell signaling or cell-to-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behaviour of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to cell signaling by endocrine factors, hormones which travel considerably longer distances via ...
https://www.ncbi.nlm.nih.gov/pubmed/29668890
Jun 01, 2018 · The use of LH supplementation in ovarian stimulation may increase gonadotropin sensitivity in small antral follicles and promote follicular growth and survival by suppressing GC apoptosis and follicular atresia, resulting in multiple follicular development, even in patients with POR. PMID: 29668890 [Indexed for MEDLINE] Publication Types:Cited by: 2
https://www.researchgate.net/publication/11913829_Cellular_basis_for_paracrine_regulation_of_ovarian_follicle
Cellular basis for paracrine regulation of ovarian follicle. ... This article summarizes evidence to support a model for bi-directional paracrine communication that is based on developmental ...
https://www.britannica.com/science/paracrine-function
…the circulation, is known as paracrine function. Excellent examples of the paracrine actions of hormones are provided by the ovaries and testes. Estrogens produced in the ovaries are crucial for the maturation of ovarian follicles before ovulation. Similarly, testosterone produced by the Leydig cells of the testes acts on adjacent… Read More
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.554.2439
CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): abstract: Assisted reproductive technology has evolved on the back of blunderbuss ovarian stimulation regimes designed tomaximize the number of oocytes recoverable for treatment purposes. However, oocyte ‘quality ’ is finely programmed by local paracrine and autocrine signal-ling events during folliculogenesis and ...
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