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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707421/
Apr 11, 2013 · Perivascular support of human hematopoietic stem/progenitor cells. ... Hematopoietic stem and progenitor cells (HSPCs) emerge and develop adjacent to blood vessel walls in the yolk sac, aorta-gonad-mesonephros region, embryonic liver, and fetal bone marrow. In adult mouse bone marrow, perivascular cells shape a “niche” for HSPCs.Cited by: 152
https://www.ncbi.nlm.nih.gov/pubmed/23412095
Apr 11, 2013 · Perivascular support of human hematopoietic stem/progenitor cells. Corselli M(1), Chin CJ, Parekh C, Sahaghian A, Wang W, Ge S, Evseenko D, Wang X, Montelatici E, Lazzari L, Crooks GM, Péault B. Author information: (1)Orthopaedic Hospital, Department of Orthopaedic Surgery, University of California at Los Angeles (UCLA), CA, USA.Cited by: 152
https://www.cirm.ca.gov/about-cirm/publications/perivascular-support-human-hematopoietic-stemprogenitor-cells
The identity of the subset of human MSCs involved in hematopoietic support has been so far unknown. In the present study, Corselli et al. identified for the first time CD146+ perivascular cells as the subset of MSCs able to maintain hematopoietic stem and progenitor cells (HSPCs) after ex vivo culture.
https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(08)00337-8
Sep 11, 2008 · Mesenchymal stem cells (MSCs), the archetypal multipotent progenitor cells derived in cultures of developed organs, are of unknown identity and native distribution. We have prospectively identified perivascular cells, principally pericytes, in multiple human organs including skeletal muscle, pancreas, adipose tissue, and placenta, on CD146, NG2, and PDGF-Rβ expression and absence of ...Cited by: 3387
https://www.researchgate.net/publication/235629319_Perivascular_support_of_human_hematopoietic_cells
Hematopoietic stem and progenitor cells (HSPCs) emerge and develop adjacent to blood vessel walls in the yolk sac, aorta-gonad-mesonephros region, embryonic liver, and fetal bone marrow (FBM).
https://www.cirm.ca.gov/printpdf/16211
Mesenchymal stem/stromal cells (MSCs), which support hematopoiesis in culture, are themselves derived in part from perivascular cells. In order to define their direct role in hematopoiesis, we tested the ability of purified human CD146(+) perivascular cells, as compared with unfractionated MSCs and CD146(-) cells, to sustain human HSPCs in ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707421/
Apr 11, 2013 · Perivascular support of human hematopoietic stem/progenitor cells. ... Hematopoietic stem and progenitor cells (HSPCs) emerge and develop adjacent to blood vessel walls in the yolk sac, aorta-gonad-mesonephros region, embryonic liver, and fetal bone marrow. In adult mouse bone marrow, perivascular cells shape a “niche” for HSPCs.Cited by: 152
https://www.ncbi.nlm.nih.gov/pubmed/23412095
Apr 11, 2013 · Mesenchymal stem/stromal cells (MSCs), which support hematopoiesis in culture, are themselves derived in part from perivascular cells. In order to define their direct role in hematopoiesis, we tested the ability of purified human CD146(+) perivascular cells, as compared with unfractionated MSCs and CD146(-) cells, to sustain human HSPCs in ...Cited by: 152
https://www.cirm.ca.gov/about-cirm/publications/perivascular-support-human-hematopoietic-stemprogenitor-cells
The identity of the subset of human MSCs involved in hematopoietic support has been so far unknown. In the present study, Corselli et al. identified for the first time CD146+ perivascular cells as the subset of MSCs able to maintain hematopoietic stem and progenitor cells (HSPCs) after ex vivo culture.
http://europepmc.org/abstract/MED/23412095
May 01, 2013 · Moreover, CD146(+) perivascular cells express, natively and in culture, molecular markers of the vascular hematopoietic niche. Unexpectedly, this dramatic, previously undocumented ability to support hematopoietic stem cells is present in CD146(+) perivascular cells extracted from the nonhematopoietic adipose tissue.Cited by: 152
https://www.researchgate.net/publication/235629319_Perivascular_support_of_human_hematopoietic_cells
Hematopoietic stem and progenitor cells (HSPCs) emerge and develop adjacent to blood vessel walls in the yolk sac, aorta-gonad-mesonephros region, embryonic liver, and fetal bone marrow (FBM).
http://www.crm.ed.ac.uk/publications/perivascular-support-human-hematopoietic-stem/progenitor-cells
Mesenchymal stem/stromal cells (MSCs), which support hematopoiesis in culture, are themselves derived in part from perivascular cells. In order to define their direct role in hematopoiesis, we tested the ability of purified human CD146(+) perivascular cells, as compared with unfractionated MSCs and CD146(-) cells, to sustain human HSPCs in ...
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