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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621483/
Sorbitol is an acyclic polyol that is commonly used as an osmotic stabilizer, but has not been previously examined for effects on survival and adaptation to osmotic stress in C. elegans. Similar to the effect of 10X peptone, addition of 5% sorbitol (275 mM) to the NGM resulted in a significant lifespan extension (Figure (Figure1B). 1B).Cited by: 10
http://www.plantphysiol.org/content/121/1/45
Sep 01, 1999 · If osmotic adjustment by glycerol were the only requirement for successful adaptation, an equal concentration of sorbitol or mannitol would be expected to confer the same tolerance. This interpretation was also supported by comparing the gpd strain …
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/sorbitol
This is known as the osmotic hypothesis, aldose reductase hypothesis, or sorbitol hypothesis. This hypothesis is supported by extensive studies utilizing AR inhibitors (ARIs), animal models, and in vitro lens culture studies. 18,19 Prevention studies utilizing a broad range of structurally diverse ARIs demonstrate that sugar cataracts can be dose-dependently delayed or inhibited.
http://www.protocol-online.org/biology-forums/posts/41395.html
What is "osmotic support"? - (Nov/22/2008 ) Does anyone know this? Why sorbitol can provide osmotic support to cells with weakened cell wall?-dv6000t-Have a look here. Is that helpful?-HomeBrew-QUOTE (HomeBrew @ Nov 22 2008, 07:57 PM) Have a look here. Is that helpful?
https://ejournal.sinica.edu.tw/bbas/content/1999/3/bot403-07.html
The effects of osmotic stress induced by 0.6 M sorbitol on the cell growth and on the quantitative and qualitative changes in carbohydrates and free amino acids in suspended cells of sweet potato (Ipomoea batatas) were analyzed. Cells transferred into medium without (normal treatment) or with (stress-shocked treatment) 0.6 M sorbitol added, and ...Cited by: 95
https://www.researchgate.net/publication/229777961_Sorbitol_a_compatible_osmotic_solute_in_Plantago_maritima
The osmotic stress condition was evaluated by varying the sorbitol concentration from 100 to 300 mM. As can be seen in Fig. 8A and C, the wild type and engineered Synechocystis were more tolerant ...
https://www.drugs.com/sfx/sorbitol-side-effects.html
Sep 18, 2019 · Applies to sorbitol: compounding powder, irrigation solution, oral liquid. Gastrointestinal. Gastrointestinal side effects have included sudden severe abdominal bloating, abdominal cramping, vomiting, and osmotic diarrhea. Metabolic. Metabolic side effects have included reports of …9/10
https://www.ncbi.nlm.nih.gov/pubmed/10482659
Sorbitol and mannitol provided some protection, but less than that generated by a similar concentration of glycerol generated by glycerol-3-P dehydrogenase (GPD1). Reduced protection by polyols suggested that glycerol had specific functions for which mannitol and sorbitol could not substitute, and that the absolute amount of the accumulating osmoticum might not be crucial.Cited by: 199
https://www.sigmaaldrich.com/catalog/product/sigma/s1876
May be used to induce osmotic stress. Biochem/physiol Actions D-Sorbitol is a sugar alcohol that is commonly used as a sugar substitute. It occurs naturally and is also produced synthetically from glucose. The food industry uses D-sorbitol as an additive in the form of a sweetener, humectant, emulsifier, thickener, or dietary supplement.
https://en.wikipedia.org/wiki/Sorbitol
Sorbitol works as a laxative by drawing water into the large intestine, stimulating bowel movements. Sorbitol has been determined safe for use by the elderly, although it is not recommended without the advice of a doctor. Sorbitol is found in some dried fruits and may contribute to …Chemical formula: C₆H₁₄O₆
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