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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737090/
We found that IL-10 exerts a direct trophic influence on spinal cord neurons, and that activation of the neuronal IL-10 receptor provides trophic support and survival cues to overcome the neurotoxic effects of glutamate in vitro.Cited by: 120
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750745/
May 14, 2009 · Astrocytes have long been considered as just providing trophic support for neurons in the central nervous system, but recently several studies have highlighted their importance in many functions such as neurotransmission, metabolite and electrolyte homeostasis, cell signaling, inflammation, and synapse modulation.Cited by: 119
https://www.jneurosci.org/content/17/6/1959
Mar 15, 1997 · Trophic support by neuronal afferents can involve neurotrophic factors, cAMP, and membrane electrical activity. SGNs die after deafferentation in vivo and after isolation in culture.Cited by: 265
https://www.pnas.org/content/pnas/81/19/6245.full.pdf
the trophic support ofDRG neurons or, alternatively, that the loss ofa postsynaptically derivedtrophic substancefrom the central terminal zones can be sufficiently replaced by trophic agents from the peripheral target cells to keep theCited by: 164
https://molecularneurodegeneration.biomedcentral.com/articles/10.1186/1750-1326-6-40
Jun 07, 2011 · Pleiotrophin is known to promote the survival and differentiation of dopaminergic neurons in vitro and is up-regulated in the substantia nigra of Parkinson's disease patients. To establish whether pleiotrophin has a trophic effect on nigrostriatal dopaminergic neurons in vivo, we injected a recombinant adenovirus expressing pleiotrophin in the substantia nigra of 6-hydroxydopamine …Cited by: 22
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