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https://alsnewstoday.com/2016/09/22/respiratory-support-in-ALS-patients-may-decrease-quality-of-life
Sep 22, 2016 · Most patients with amyotrophic lateral sclerosis (ALS) develop respiratory problems in the advanced stage of their disease and are put on chronic ventilator support to improve their symptoms. Now a new study shows that despite improved respiration, the patients’ quality of life may worsen over time.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361018/
Nov 01, 2013 · ALS selectively causes degeneration in upper and lower (spinal) motor neurons, leading to muscle weakness, paralysis and death by ventilatory failure. Although ventilatory failure is generally the cause of death in ALS, little is known concerning the impact of …Cited by: 26
https://openres.ersjournals.com/content/5/suppl_3/P25
Apr 11, 2019 · Amyotrophic Lateral Sclerosis (ALS) represents the most common and severe motor neuron disease, with inevitable respiratory failure development. Ventilatory support (VS) has shown a valuable prognostic impact, even in bulbar-onset ALS. To analyse, ALS patients` outcomes related with VS, phenotypes or functional parameters, a prospective study was conducted in 81 patients, with …Author: Bebiana Da Conceição Fernandes Palheiros Conde, Natália Martins, Elsa Matos, Inês Rodrigues, João Ca...
https://www.mypcnow.org/fast-fact/management-of-respiratory-failure-in-als/
During the day bi-level support can be used to alleviate respiratory muscle fatigue. The use of ‘intermittent positive pressure’ breathing machines has been reported to expand the lungs and reduce atelectasis. Full-time invasive ventilatory support is considered when non-invasive ventilation is no longer effective or tolerable.
http://www.jneuropsychiatry.org/peer-review/ventilatory-support-outcomes-in-amyotrophic-lateral-sclerosis-als-patients-12934.html
Ventilatory support, Amyotrophic lateral sclerosis, Survival, Respiratory function Introduction Amyotrophic Lateral Sclerosis (ALS) is a rare, progressive neurodegenerative and fatal disease.Author: Bebiana Conde, Natalia Martins, Joao Carlos Winck
https://www.alstexas.org/understanding-als/als-symptoms/
When the breathing muscles become affected, the patient will ultimately need permanent ventilatory support in order to survive. Because ALS attacks only motor neurons, the sense of sight, touch, hearing, taste and smell are not affected at any stage of the disease. For many people, muscles of the eyes and bladder will also generally not be affected.
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