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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649611/
The fact that liver failure constitutes a life-threatening condition and can, in most cases, only be overcome by orthotopic liver transplantation, lead to the development of various artificial and bioartificial liver support devices. While artificial systems are based on the principles of adsorption and filtration, the more complex concept of bioartificial devices includes the provision of liver cells.
https://www.amazon.com/Artificial-Liver-Support-Concepts-Methods/dp/3642773613
There therefore continues to be a great need for the development of other forms of artificial liver support. Improved intensive care utilizing improved plasma exchange, dialysis, sclerotherapy, and intracranial pressure monitoring have improved survival in fulminant hepatic failure.Author: G. Brunner
https://journals.lww.com/co-criticalcare/Abstract/2019/04000/Artificial_liver_support_in_acute_and.16.aspx
Liver failure is a life-threatening condition, and an artificial liver is highly desirable to replace the failing liver-functions in the waiting time for liver regeneration to happen or until liver transplantation can be undertaken. This review focuses on the efficacy of using artificial extracorporeal liver support …
https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-018-0453-z
Nov 15, 2018 · Some of the substances removed by the different artificial hepatic support systems include conjugate or unconjugated bilirubin or protoporphyrin, bile acids, glycoside derivatives, phenols, short- and medium-chain fatty acids, such as octanoate, or heterocyclic organic compounds.Cited by: 3
https://www.sciencedirect.com/science/article/pii/B9780123985231000239
In Suzhou, China, Gan et al. tested another Hybrid Artificial Liver Support System (HALSS) in 10 patients suffering severe liver failure . This system differs from HBAL in that it includes a hemo-adsorba column, to remove bilirubin and toxins and because the bioreactor is …Author: Xavier Wittebole, Diego Castanares-Zapatero, Christine Collienne, Olga Ciccarelli, Philippe Hantson,...
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