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https://www.drugs.com/drug-class/colony-stimulating-factors.html
Colony stimulating factors are glycoproteins that promote production of white blood cells (mainly granulocytes such as neutrophils), in response to infection. Administration of exogenous colony stimulating factors stimulates the stem cells in the bone marrow to produce more of …
http://www.med.umich.edu/1libr/RogelCancerCenter/GrowthFactorSupport.pdf
Granulocyte Colony-Stimulating Factor (GCSF) Support . What are GCSF medications? GCSF medications stimulate bone marrow to produce white blood cells. What are these medications used for? Our bodies need white blood cells to fight infection. Chemotherapy can affect the bone marrow and reduce the number of these white cells. This increases the
https://www.uptodate.com/contents/use-of-granulocyte-colony-stimulating-factors-in-adult-patients-with-chemotherapy-induced-neutropenia-and-conditions-other-than-acute-leukemia-myelodysplastic-syndrome-and-hematopoietic-cell-transplantation
Colony-stimulating factors for febrile neutropenia during cancer therapy. N Engl J Med 2013; 368:1131. Lyman GH, Dale DC, Culakova E, et al. The impact of the granulocyte colony-stimulating factor on chemotherapy dose intensity and cancer survival: a systematic review and meta-analysis of randomized controlled trials. Ann Oncol 2013; 24:2475.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918448/
The Colony-Stimulating Factors. The CSFs were discovered because granulocyte and macrophage colony formation in semi-solid cultures in vitro is absolutely dependent on the presence of CSFs in the culture. Initially, it was thought that there would be only one type of CSF and that this would be the regulator of granulocytes and macrophages ...Cited by: 12
https://www.uhcprovider.com/content/dam/provider/docs/public/policies/medadv-guidelines/c/colony-stimulating-factors.pdf
Sargramostim/Leukine® is a synthetic granulocyte-macrophage colony-stimulating factor (GM-CSF) produced by recombinant DNA technology in S. cerevisiae yeast. Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) is an antineutropenic, hematopoietic growth factor, which supports survival, clonal expansion, and differentiation of
https://en.wikipedia.org/wiki/Colony-stimulating_factor
Colony-stimulating factors (CSFs) are secreted glycoproteins that bind to receptor proteins on the surfaces of hemopoietic stem cells, thereby activating intracellular signaling pathways that can cause the cells to proliferate and differentiate into a specific kind of blood cell (usually white blood cells.For red blood cell formation, see erythropoietin).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195572/
Jul 19, 1999 · We demonstrated previously that a single injection of recombinant human macrophage colony-stimulating factor (rhM-CSF) is sufficient for osteoclast recruitment and survival in osteopetrotic (op/op) mice with a deficiency in osteoclasts resulting from a mutation in M-CSF gene.In this study, we show that a single injection of recombinant human vascular endothelial growth factor (rhVEGF) can ...Cited by: 602
https://www.macmillan.org.uk/information-and-support/treating/supportive-and-other-treatments/supportive-therapies/g-csf.html
Nov 30, 2018 · G-CSF (granulocyte-colony stimulating factor) is a type of drug called a growth factor. It increases the number of some types of blood cells in the blood. It can be used with chemotherapy. It can also be used before and after a stem cell transplant. Different types of G-CSF can be used. These include: lenograstim (Granocyte ®)
https://en.wikipedia.org/wiki/M-CSF
The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which causes hematopoietic stem cells to differentiate into macrophages or other related cell types. Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection. It is one of the three experimentally described colony-stimulating factors.Aliases: CSF1, CSF-1, MCSF, colony stimulating factor 1
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