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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893753/
Continuous positive airway pressure (CPAP) trial using a CPAP level equal to the previous positive end-expiratory pressure (PEEP) level. Invasive ventilation with low level of pressure support (5-8 cmH2O) or automatic tube compensation. There is no current evidence suggesting that one of these approaches is superior to the others (22, 23).Cited by: 3
http://pocketicu.com/index.php/2017/02/24/ventilator-weaning/
Mar 25, 2019 · Weaning failure is defined as the failure to pass a spontaneous-breathing trial or the need for reintubation within 48 hours following extubation. What is a sponteous breathing trial: Quite frequently, we hear that patients are placed on a pressure support or CPAP and that they passed a spontaneous breathing trial.
https://www.sciencedirect.com/topics/medicine-and-dentistry/spontaneous-breathing-trial
Continuous positive airway pressure (CPAP) with pressure support is the preferred initial mode for weaning patients with respiratory muscle weakness. Each time the patient inhales, “pressure support” delivers additional inspiratory volume until a preset level of pressure is reached.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762048/
More recently, a study described that replacing CPAP with nasal cannulae oxygen increased the duration of respiratory support without increasing success of weaning. A combination of change in randomization method and the trial stopping early for efficacy led to an imbalance in the number of subjects in each intervention group in this trial.
https://www.wfsahq.org/components/com_virtual_library/media/638e81d0a0cb0d857a0f6327973d643c-372-Weaning-from-ventilator.pdf
A study comparing the RSBI value in patients on pressure support versus continuous positive airway pressure (CPAP) versus a T-piece trial showed, not surprisingly, that the value of RSBI is significantly altered by the mode of ventilatory support that a patient is on when the RSBI is measured.
https://clinicaltrials.gov/ct2/show/NCT01215591
Trial of Weaning of Nasal Continuous Positive Airway Pressure (CPAP) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
https://www.sciencedirect.com/science/article/pii/S0964339705000704
Different systems are available to provide CPAP to weaning patients, CPAP can be used while the patient is attached to a ventilator and is allowed to breathe spontaneously without the aid of ventilator breaths but a positive airway pressure is maintained (Geisman, 1989, Epstein, 2001).Cited by: 4
https://litfl.com/spontaneous-breathing-trial/
Sep 14, 2019 · Sassoon CS, Light RW, Lodia R, Sieck GC, Mahutte CK. Pressure-time product during continuous positive airway pressure, pressure support ventilation, and T-piece during weaning from mechanical ventilation. Am Rev Respir Dis. 1991 Mar;143(3):469-75. PubMed PMID: 2001053. Tobin MJ. Extubation and the myth of “minimal ventilator settings”.
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