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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356396/
The most promising nonbiologic support therapies combine detoxification of water-soluble and protein-bound toxins in a dialysis system, such as the Molecular Adsorbents Recirculating System (MARS), 29–32 the albumin dialysis system, 33 the Artificial Liver …Cited by: 268
https://www.science20.com/news_articles/elad_artificial_liver_uses_human_liver_cells
ELAD, the Extracorporeal Liver Assist Device, is a bedside system that treats blood plasma, metabolizing toxins and synthesizing proteins just like a real liver does. Artificial livers have been attempted since the 1960s but because previous designs didn't use human liver cells, they couldn't adequately filter toxins or create chemicals essential to metabolism and blood-clotting.
https://www.cedars-sinai.org/newsroom/researchers-testing-artificial-liver-as-potential-therapy-for-patients-with-alcohol-related-organ-failure/
Sep 22, 2014 · ELAD® investigational bio-artificial liver support system (click for larger image) In the bioartificial liver under investigation, blood is drawn from the patient via a central venous line, and then is filtered through a component system featuring four tubes, each …
https://clinicaltrials.gov/ct2/show/NCT01471028
ELAD treatment consists of treatment with an extracorporeal liver assist system.
http://www.medicalpolicy.hcsc.net/medicalpolicy/pendingPolicyPage?lid=j92nfg1i
Nov 15, 2017 · A phase 2b study of safety & efficacy of a human cell-based biological liver support system (ELAD) in subjects with acute-on-chronic hepatitis (AOCH) due either to acute alcoholic hepatitis or acute decompensation of cirrhosis.
https://www.sciencedirect.com/topics/veterinary-science-and-veterinary-medicine/liver-support-systems
Artificial liver support systems can work as a bridge for patients with severe liver disease, either to give them time to recover or to go to transplant. Many attempts have been made to develop artificial liver support devices (ALSD).
https://www.bcbst.com/mpmanual/Artificial_Liver_Assist_Devices_for_the_Treatment_of_Liver_Conditions_.htm
Liver assist devices are intended to support an individual in acute liver failure until the native liver has time to recover, or to bridge the individual to liver transplantation. This procedure may also be referred to as liver dialysis. Liver assist therapies may include cell-free artificial or bioartificial systems.
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