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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082035/
Jan 01, 2011 · Liver support therapies for acute or chronic liver failure would be instituted at the “threshold” of organ dysfunction as a bridge to recovery or transplantation. However, if the loss of liver cell function is irreversible, liver support may be considered only if the provision of a transplant within weeks to months is a realistic option.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774070/
The development of these devices has been approached in two very different ways. The biological devices, which aim to provide all of the functions of the normal liver, 3, 4 are based on the use of living liver cells with either human hepatic cells as in the extracorporeal liver assist device (ELAD) device 5 or porcine hepatocytes as in the BAL device 6 and in various other European devices ...Cited by: 93
https://en.wikipedia.org/wiki/Liver_support_systems
Liver support systems are therapeutic devices to assist in performing the functions of the liver in persons with liver damage. The primary functions of the liver include removing toxic substances from the blood, manufacturing blood proteins , storing energy in the form of glycogen , and secreting bile .Specialty: hepatology
https://clinicaltrials.gov/ct2/show/NCT01471028
Assess Safety and Efficacy of ELAD (Extracorporeal Liver Assist System) in Subjects With Alcohol-Induced Liver Failure The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.
https://www.liversupport.com/could-liver-cancer-cells-have-an-upside/
The ELAD system is a bio-artificial liver support system that operates outside the body. It is designed to allow the patient’s own liver to regenerate to a healthy state, or to stabilize the patient until a liver transplant is available.
https://www.science20.com/news_articles/elad_artificial_liver_uses_human_liver_cells
ELAD, the Extracorporeal Liver Assist Device, is a bedside system that treats blood plasma, metabolizing toxins and synthesizing proteins just like a real liver does.Artificial livers have been attempted since the 1960s but because previous designs didn't use human liver cells, they couldn't adequately filter toxins or create chemicals essential t
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