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https://www.macmillan.org.uk/information-and-support/treating/supportive-and-other-treatments/supportive-therapies/g-csf.html
Nov 30, 2018 · G-CSF stimulates the bone marrow to make more stem cells. These then move (mobilise) from the bone marrow into the bloodstream, where they can be collected to be used in a transplant. G-CSF may also be used after a stem cell transplant to help speed up the recovery of the new stem cells in the bone marrow. Collecting your stem cells
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846279/
Feb 27, 2010 · G-CSF prophylaxis is now recommended when the overall risk of febrile neutropenia (FN) due to regimen and individual patient factors is ≥20%, for supporting dose-dense and dose-intense chemotherapy and to help maintain dose density where dose reductions have been shown to compromise outcomes.Cited by: 93
https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/cancer-drugs/drugs/g-csf
Jul 18, 2019 · G-CSF is a type of growth factor that makes the bone marrow produce white blood cells to reduce the risk of infection after some types of cancer treatment. G-CSF also makes some stem cells move from the bone marrow into the blood. Stem cells are the cells in the bone marrow that make red blood cells, white cells and platelets. Before a stem cell transplant, you have G-CSF to stimulate the …
http://www.lhsc.on.ca/Health_Professionals/LRCP/Oncology_Practice_Guidelines/LRCPGCSFalgorithmneutropeniaNov07.pdf
Algorithm for White Cell Growth Factor (G-CSF) Support Step 1.Evaluate patient for risk of febrile neutropenia (FN) prior to each cycle4,5 Review:
https://www.medscape.com/viewarticle/540139_4
Oct 23, 2019 · Scheduling G-CSF Support With Dose-dense Chemotherapy The timing and duration of G-CSF support are crucial to the optimal administration of dose …
https://www.researchgate.net/publication/323409131_Bendamustine_and_G-CSF_support
High dose cyclophosphamide (CY) (3-4 g/m2) and granulocyte colony stimulating factor (G-CSF) were used to mobilize peripheral blood stem cells (PBSC).
https://en.wikipedia.org/wiki/Granulocyte_colony-stimulating_factor
G-CSF is also a potent inducer of hematopoietic stem cell (HSC) mobilization from the bone marrow into the bloodstream, although it has been shown that it does not directly affect the hematopoietic progenitors that are mobilized. Neurons G-CSF can also act on neuronal cells as a neurotrophic factor.Aliases: CSF3, C17orf33, CSF3OS, GCSF, …
https://www.uptodate.com/contents/use-of-granulocyte-colony-stimulating-factors-in-adult-patients-with-chemotherapy-induced-neutropenia-and-conditions-other-than-acute-leukemia-myelodysplastic-syndrome-and-hematopoietic-cell-transplantation
The role of G-CSFs in patients with myelodysplastic syndrome, in those undergoing induction chemotherapy for acute leukemia, and in the setting of HCT is addressed elsewhere, as are the potential side effects of CSFs (eg, bone pain, risk of therapy-related myeloid neoplasms).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741374/
Aug 15, 2015 · G-CSF and/or GM-CSF may improve chemotherapy and immunotherapy of hematologic malignancies and non-blood cancers. For instance, these myeloid growth factors can recruit quiescent leukemic cells into the cell cycle for enhanced killing from cell cycle-specific chemotherapy(74, 97). As a pro-inflammatory cytokine, GM-CSF is being used to promote dendritic cell activity in a variety of anti …Cited by: 97
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