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https://clinicaltrials.gov/ct2/show/NCT03975647
This study is designed to evaluate the efficacy and safety of tucatinib in combination with T-DM1 in subjects with unresectable locally-advanced or metastatic HER2+ breast cancer who have had prior treatment with a taxane and trastuzumab in any setting.
https://www.nejm.org/doi/full/10.1056/NEJM200103153441101
Background The HER2 gene, which encodes the growth factor receptor HER2, is amplified and HER2 is overexpressed in 25 to 30 percent of breast cancers, increasing the aggressiveness of the tumor.
https://academic.oup.com/annonc/article/24/9/2278/201802
introduction. The combination of trastuzumab with pertuzumab, a humanized monoclonal antibody targeting a different epitope of HER2 from trastuzumab, was first studied in patients with HER2-positive metastatic breast cancer whose disease had progressed during previous therapy including trastuzumab [1, 2].Adverse events were mostly mild or moderate in intensity, and the combination of both ...
https://www.asco.org/research-guidelines/quality-guidelines/guidelines/gastrointestinal-cancer
ASCOconnection.org features blogs from members, the online version of the membership magazine, a discussion area, working groups, and links to the Membership Directory, Career …
https://www.mayoclinic.org/diseases-conditions/breast-cancer/in-depth/breast-cancer/art-20045654
Breast cancer types: What your type means. Not all breast cancers are the same. Understand what type of breast cancer you have and how it differs from other types of breast cancer.
https://community.breastcancer.org/
Just Diagnosed. 7,081 Topics 106,538 Posts . Discuss next steps, options, and resources. Latest post: 26 years old and just diagnosed with IDC by santabarbarian 6 hours ago Diagnosed and Waiting for Test Results. 668 Topics 7,473 Posts . Share with and support others all waiting for test results from CAT scan, PET scan, Oncotype tests, Mammaprint, FISH, IHC, and other diagnostic tests.
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