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Welcome to HER2 Support Group We are patients, caregivers, mothers, daughters, sons and husbands of breast cancer survivors who are HER2 positive. We gather here to seek information about the illness. Here you will find newly diagnosed patients and long term survivors willing to share their experiences and knowledge.
https://www.cancer.gov/news-events/cancer-currents-blog/2019/kadcyla-fda-breast-her2-adjuvant
Ado-trastuzumab, also called T-DM1, was initially approved by FDA more than 6 years ago to treat women with metastatic HER2-positive breast cancer. Under the expanded approval, it can now be used when the cancer is far less advanced: as a …
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https://www.targetedonc.com/conference/sabcs-2018/katherine-findings-support-tdm1-as-new-adjuvant-standard-in-highrisk-her2-breast-cancer
Dec 05, 2018 · Findings from the phase III KATHERINE study showed adjuvant treatment with ado-trastuzumab emtansine (T-DM1; Kadcyla) reduced the risk of invasive disease recurrence or death by 50% compared with trastuzumab (Herceptin) in patients with HER2-positive early breast cancer who had residual invasive disease following neoadjuvant therapy.
https://www.cancernetwork.com/her2-positive-breast-cancer/where-does-t-dm1-fit-first-line-treatment-her2-positive-breast-cancer
Oct 28, 2019 · “The final analysis of MARIANNE supports the use of T-DM1 as a first-line treatment option for certain patients with HER2-positive metastatic breast cancer,” the authors concluded, adding that T-DM1 may be best suited for patients ineligible to …Author: Dave Levitan
https://www.nejm.org/doi/full/10.1056/NEJMoa1814017
Trastuzumab Emtansine in Residual Breast Cancer Residual cancer after induction therapy for HER2-positive breast cancer is associated with a worse …Cited by: 172
https://www.cancernetwork.com/her2-positive-breast-cancer/trial-results-support-frontline-use-t-dm1-her2positive-metastatic-breast-cancer
Oct 28, 2019 · Treatment with trastuzumab emtansine (T‐DM1; Kadcyla) demonstrated similar overall survival (OS) across 3 treatment arms, with each resulting in a median OS longer than 50 months, among patients with HER2‐positive metastatic breast cancer, according to the final analysis of the phase 3 MARIANNE trial.Author: Kristie L. Kahl
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