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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691094/
Dec 04, 2015 · Inotropes can be used in patients with severe systolic heart failure awaiting heart transplant to maintain hemodynamic stability or as a bridge to decision. In cases where patients are unable to be weaned off inotropes, these agents can be used until a definite or escalated supportive therapy is planned,...Cited by: 30
https://www.cfrjournal.com/articles/Inotropes-in-Acute-Heart-Failure
Apr 20, 2019 · Inotropes are pharmacological agents that are indicated for the treatment of patients presenting with acute heart failure (AHF) with concomitant hypoperfusion due to decreased cardiac output. They are usually administered for a short period during the initial management of AHF until haemodynamic stabilisation and restoration of peripheral perfusion occur.Author: Ignatios Ikonomidis, John Parissis, Vasiliki Bistola, Angelos Arfaras-Melainis, Eftihia Polyzogopoul...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861129/
Apr 13, 2010 · Systolic heart failure (HF) is a systemic disease caused by reduced cardiac contractility. Though it would seem logical that this disease could be treated by employing strategies to directly improve contractility, inotropic therapies in the HF population have universally failed to …Cited by: 59
https://www.uptodate.com/contents/inotropic-agents-in-heart-failure-with-reduced-ejection-fraction
May 25, 2018 · Positive inotropic agents used to treat heart failure with reduced ejection fraction (HFrEF) include intravenous phosphodiesterase (PDE)-3 inhibitors (eg, milrinone), beta adrenergic receptor agonists (eg, dobutamine), intravenous calcium-sensitizing agents (eg, levosimendan, available in some countries outside the United States), and digoxin (available in oral and intravenous forms) . All …
https://optioncare.com/home-infusion-inotropic-therapy-helps-heart-failure-patients-enjoy-better-quality-life-option-care-research-shows/
Jul 12, 2017 · The study included 88 adult heart failure patients who filled out the Minnesota Living with Heart Failure Questionnaire (MLHFQ) before the start of inotropic infusion and three months after home infusion of the therapy.1 The MLHFQ measures the effect of heart failure on quality of life by asking patients 21 questions on issues ranging from shortness of breath to medical costs.
https://www.ahajournals.org/doi/abs/10.1161/circulationaha.109.899294
20 Metra M, Nodari S, D'Aloia A, Muneretto C, Robertson AD, Bristow MR, Dei Cas L. Beta-blocker therapy influences the hemodynamic response to inotropic agents in patients with heart failure: a randomized comparison of dobutamine and enoximone before …Cited by: 59
https://healthjade.net/inotropic/
Positive inotropic drugs are used to treat congestive heart failure and heart rhythm problems (atrial arrhythmias). Positive inotropic drugs can increase blood flow throughout your body and reduce swelling in your hands and ankles.
https://www.texasheart.org/heart-health/heart-information-center/topics/inotropic-agents/
Positive inotropes strengthen the heart’s contractions, so it can pump more blood with fewer heartbeats. This medicine is usually given to patients with congestive heart failure or cardiomyopathy. These medicines may also be given to patients who have had a recent heart attack.
https://www.drugs.com/drug-class/inotropic-agents.html
Inotropes are given for conditions associated with a low cardiac output (CO) (poor heart contraction), such as cardiogenic shock following a heart attack, severe heart failure, or following cardiac surgery. If left untreated, tissues become starved of oxygen, resulting in the formation of lactic acid and subsequent organ failure and death.
https://en.wikipedia.org/wiki/Inotrope
Negative inotropic agents decrease myocardial contractility and are used to decrease cardiac workload in conditions such as angina. While negative inotropism may precipitate or exacerbate heart failure, certain beta blockers (e.g. carvedilol, bisoprolol and metoprolol) have been believed to reduce morbidity and mortality in congestive heart failure.
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