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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495871/
Although the role of inotropes during the initial resuscitation phase of septic-shock patients may be diminished, a recent consensus statement on circulatory shock and hemodynamic monitoring published by the European Society of Intensive Care Medicine suggests initiation of inotropes when altered cardiac function is accompanied by inadequate cardiac output and signs of tissue hypoperfusion that persist …Cited by: 4
https://journals.lww.com/ccmjournal/Abstract/2004/11001/Vasopressor_and_inotropic_support_in_septic_shock_.4.aspx
Objective: In 2003, critical care and infectious disease experts representing 11 international organizations developed management guidelines for vasopressor and inotropic support in septic shock that would be of practical use for the bedside clinician, under the auspices of the Surviving Sepsis Campaign, an international effort to increase awareness and to improve outcome in severe sepsis.
https://reference.medscape.com/medline/abstract/15542956
OBJECTIVE: In 2003, critical care and infectious disease experts representing 11 international organizations developed management guidelines for vasopressor and inotropic support in septic shock...
http://www.surgicalcriticalcare.net/Guidelines/Vasopressors%20and%20Inotropes%20in%20Shock.pdf
VASOPRESSOR AND INOTROPE USAGE IN SHOCK SUMMARY Shock is characterized by inadequate tissue perfusion, resulting in life-threatening impairment of oxygen and nutrient delivery. Treatment of shock consists of identifying and reversing the underlying pathogenesis and correcting hemodynamic abnormalities.
https://www.thecardiologyadvisor.com/home/decision-support-in-medicine/cardiology/interventional-pharmacology-inotropes-and-vasopressors/
Inotropes and/or vasopressors are essential in the management of cardiogenic shock complicating myocardial infarction/ischemia and in the treatment of hemodynamic instability occurring during coronary interventions.
https://www.pharmaceutical-journal.com/learning/learning-article/use-of-inotropes-in-critical-care/11049283.fullarticle
Inotropes are indicated in acute conditions where there is low cardiac output (CO), such as cardiogenic shock following myocardial infarction, acute decompensated …
https://emedicine.medscape.com/article/152191-medication
Aug 06, 2019 · Cardiogenic shock is a physiologic state in which inadequate tissue perfusion results from cardiac dysfunction, most often systolic. It is a major, and frequently fatal, complication of a variety of acute and chronic disorders, occurring most commonly following acute myocardial infarction (MI).
https://litfl.com/inotropes-vasopressors-and-other-vasoactive-agents/
Apr 08, 2019 · Vasoactive agents include the following: inotropes are agents that increase myocardial contractility (inotropy) — e.g. adrenaline, dobutamine, isoprenaline, ephedrine. vasopressors are agents that cause vasoconstriction leading to increased …
https://www.drugs.com/drug-class/inotropic-agents.html
Inotropes are given for conditions associated with a low cardiac output (CO) (poor heart contraction), such as cardiogenic shock following a heart attack, severe heart failure, or following cardiac surgery. If left untreated, tissues become starved of oxygen, resulting in the formation of lactic acid and subsequent organ failure and death.
https://en.wikipedia.org/wiki/Inotrope
An inotrope[help 1] is an agent that alters the force or energy of muscular contractions. Negatively inotropic agents weaken the force of muscular contractions. Positively inotropic agents increase the strength of muscular contraction. The term inotropic state is most commonly used in reference to various drugs that affect the strength of contraction of heart muscle. However, it can also refer to pathological …
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