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https://pubs.acs.org/doi/abs/10.1021/ja9635443
Site-Selective N-Methylation of Peptides on Solid Support. Stephen C. Miller; ... N-Methylation of Peptides on Selected Positions during the Elongation of the Peptide Chain in Solution Phase. ... Optimized selectiveN-methylation of peptides on solid support. Journal of Peptide Science 2006, 12 (3) , 213-219. DOI: 10.1002/psc.711. ...Cited by: 248
https://pubs.acs.org/doi/suppl/10.1021/ja9635443/suppl_file/ja2301.pdf
Site-Selective N-Methylation of Peptides on Solid Support Supplementary Material. Stephen C. Miller* and Thomas S. Scanlan Starting Materials Fmoc-amino acids and HBTU were purchased from Advanced Chemtech. Rink Amide MBHA resin was purchased from Novabiochem. Collidine, 2-
https://www.researchgate.net/publication/7574306_Optimized_selectiveN-methylation_of_peptides_on_solid_support
The procedure was based on the well known solid-phase N-methylation of N(alpha)-arylsulfonyl peptides, which was improved by using dimethylsulfate and the less expensive DBU as base.
https://www.ncbi.nlm.nih.gov/pubmed/16189816
An efficient and practical three-step procedure for selective N-methylation of peptides on solid support is described. The procedure was based on the well known solid-phase N-methylation of N(alpha)-arylsulfonyl peptides, which was improved by using dimethylsulfate and the less expensive DBU as base.Cited by: 125
https://ohsu.pure.elsevier.com/en/publications/site-selective-n-methylation-of-peptides-on-solid-support-2
Miller, SC & Scanlan, TT 1997, ' Site-selective N-methylation of peptides on solid support ', Journal of the American Chemical Society, vol. 119, no. 9, pp. 2301-2302 ...Cited by: 248
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720131/
Jan 15, 2016 · A strategy that has been used with success both in nature and by chemists for enhancing the affinity, selectivity, and activity of small peptides is N-methylation. 20,21 Nucleic acid binding natural products such as echinomycin, 22 the original inspiration for our resin-bound library design, incorporate N-methylation, and some of the highest affinity synthetic RNA binders known are N-methyl ...Cited by: 23
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