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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419094/
May 08, 2015 · Hyperammonemia can be toxic with signs and symptoms that include: episodic irritability, vomiting, ataxia, mental retardation, and lethargy that can progress to alteration of consciousness and coma[13,14]. Both acute and chronic hyperammonemia alters the brain neurotransmitter system.Cited by: 8
https://www.carbaglu.net/hcp/diagnosing-nags/
Signs and symptoms of hyperammonemia due to NAGS deficiency. The brain is the main organ affected by hyperammonemia caused by NAGS deficiency (NAGSD) or other inherited metabolic urea cycle disorders (UCDs). Most signs and symptoms are neurological in origin. 1. Review emergency management instructions for hyperammonemic crisis
https://www.sciencedirect.com/topics/medicine-and-dentistry/hyperammonemia
Hyperammonemia, characterized by excess ammonia in the blood, can be a life-threatening condition. Clinical symptoms are nonspecific, and include poor feeding, lethargy, irritability, tachypnea, seizures, obtundation, and respiratory insufficiency. Hyperammonemia is due to defect in detoxification or overproduction of ammonia.
https://rarediseases.info.nih.gov/diseases/9931/hyperinsulinismhyperammonemia-syndrome
Apr 01, 2015 · Hyperinsulinism-hyperammonemia syndrome (HIHA) is a frequent form of diazoxide-sensitive diffuse hyperinsulinism (see this term), characterized by an excessive/ uncontrolled insulin secretion (inappropriate for the level of glycemia), asymptomatic hyperammonemia and recurrent episodes of profound hypoglycemia induced by fasting and protein rich meals, requiring rapid and …
https://www.babysfirsttest.org/newborn-screening/conditions/hyperornithinemia-hyperammonemia-homocitrullinuria-syndrome
Support groups can help connect families who have a child or other family member affected with hyperornithinemia-hyperammonemia-homocitrullinuria syndrome (HHH) with a supportive community of people who have experience and expertise in living with the condition.
https://www.ravicti.com/about-urea-cycle-disorders/what-is-hyperammonemia
Any of these signs and symptoms could mean that you need to lower the amount of ammonia in your blood. If you or your loved one have any of these signs and symptoms, you may be at risk for a hyperammonemic crisis.A hyperammonemic crisis is when there …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575055/
Jul 01, 2012 · In support, the only study that measured ammonia concentrations regardless of symptoms observed a similar high frequency of hyperammonemia: 7 out of 10 patients described by Steiner et al. reached ammonia concentrations >100 μmol/L 1 day after l-asparaginase administration (Steiner et al. 2007). However, these patients all remained without ...Cited by: 26
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