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https://www.drugs.com/drug-class/inotropic-agents.html
Inotropic agents are a group of medicines that affect the contraction of the heart muscle. Technically, inotropes can be divided into positive inotropes, which stimulate and increase the force of contraction of the heart muscle, and negative inotropes, which weaken the force of muscular contractions, decreasing how hard the heart has to work.
https://www.texasheart.org/heart-health/heart-information-center/topics/inotropic-agents/
Inotropic agents, or inotropes, are medicines that change the force of your heart's contractions. Positive inotropes strengthen the force of the heartbeat. Negative inotropes weaken the force of the heartbeat. Both kinds are used in the treatment of many different cardiovascular conditions.
https://www.ncbi.nlm.nih.gov/pubmed/7686461
Inotropic support of the critically ill patient. A review of the agents. Kulka PJ(1), Tryba M. Author information: (1)Universitätsklinik für Anaesthesiologie, Intensiv- und Schmerztherapie, Berufsgenossenschaftliche Krankenanstalten Bergmannsheil, Bochum, Federal Republic of Germany.Cited by: 31
https://www.thecardiologyadvisor.com/home/decision-support-in-medicine/cardiology/interventional-pharmacology-inotropes-and-vasopressors/
In the presence of severe hypotension, beta-2 induced peripheral vasodilation may be harmful and the addition of vasoconstrictors, such as dopamine or norepinephrine, may be necessary to support the blood pressure. Phosphodiesterase inhibitors. The hemodynamic actions of milrinone result from a combination of inotropic and vasodilating properties.
https://healthjade.net/inotropic/
Positive inotropic drugs strengthen the force of the heartbeat. Negative inotropic drugs weaken the force of the heartbeat. Both kinds of inotropic agents are used in the treatment of many different cardiovascular conditions. The kind of inotropic medication …
https://www.pharmaceutical-journal.com/learning/learning-article/use-of-inotropes-in-critical-care/11049283.fullarticle
It is sometimes used for bradycardic patients requiring inotropic support. Noradrenaline. Because noradrenaline acts primarily via a 1 receptors, it is usually used as a vasopressor (increasing SVR to maintain MAP) rather than an inotrope. It is often used with other inotropes, such as dobutamine, to maintain adequate perfusion, as discussed ...
https://globalrph.com/drugs/vasopressors-and-inotropes/
Used to support BP, CO and renal perfusion in shock. IMPORTANT NOTE: Renal shutdown may occur at doses greater than 50 micrograms/kilogram/minute. The infusion rate should be reduced if urine flow decreases without adequate peripheral effects. Administer into large vein to prevent the possibility of extravasation (central line administration).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413841/
Despite widespread use, the evidence base for the use of inotropes and vasopressors in critically ill patients is limited. Clearly, many patients would not survive without inotropic support, but there is, nonetheless, considerable variation in clinical practice.Cited by: 115
https://medical-dictionary.thefreedictionary.com/inotropic
inotropic: [ in″o-trop´ik ] affecting the force of muscular contractions.
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