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https://www.ncbi.nlm.nih.gov/pubmed/11571783
A role for oligodendrocyte-derived IGF-1 in trophic support of cortical neurons. Wilkins A(1), Chandran S, Compston A. Author information: (1)Cambridge Centre for Brain Repair, Cambridge, UK. [email protected] Neurons and glia interact in the development of mammalian central nervous systems and in the maintenance of stable myelinated axons.Cited by: 217
https://www.news-medical.net/life-sciences/Oligodendrocyte-Progenitor-Cells-Production-and-Uses.aspx
Jul 09, 2019 · Oligodendrocytes are involved in the myelination of the axons, which in turn improves the function of the nerves and offers trophic support to longer axons.
https://www.ahajournals.org/doi/10.1161/str.49.suppl_1.16
Results: Oligodendrocytes were remarkably resistant to ischemic insult in the neonatal brain up to 7 days after injury; no change in oligodendrocyte precursor or mature oligodendrocyte cell count following neonatal stroke, compared to the significant loss of oligodendrocytes following adult stroke. In contrast, large numbers of TUNEL+ neurons ...Author: Christian Schroeder, Dylan Verden, Hirokazu Hashimoto, Richard J Traystman, Wendy B Macklin, Paco S ...
https://www.sciencedirect.com/topics/neuroscience/oligodendrocyte
Apart from their myelinating function, oligodendrocytes also provide trophic support to neuronal cells by releasing lactate. ... (MCT 1), which can deliver lactate, pyruvate, and ketone bodies to the axon. Oligodendrocyte precursor cells (OPCs) are present in the adult …
https://www.nature.com/articles/cddis2013335
Sep 12, 2013 · Oligodendrocytes form myelin sheaths around axons that are essential for the high-speed transmission of electrical impulses 1 and for providing trophic support to axons. 2 Damage to ...Cited by: 22
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669561/
Sep 01, 2017 · Alternatively, promoting specific changes in the expression of the genes involved in oligodendrocyte axonal support could also affect oligodendrocyte energy homeostasis and in turn promote the maintenance of the myelin sheath, which would therefore not impede the flow of trophic support from oligodendrocyte to neuron.Cited by: 58
https://www.nature.com/articles/nrn2797
Mar 10, 2010 · Myelination and the trophic support of long axons. ... D. M. et al. Genetic and physiological evidence that oligodendrocyte gap junctions contribute to spatial buffering of …Cited by: 456
https://www.wingsforlife.com/en/latest/how-does-an-oligodendrocyte-work-784/
How does an oligodendrocyte work? ... Their main functions are to provide trophic and functional support and to form the insulation of the axons (the long projections of neurons; see last month's guide). Oligodendrocytes do this by creating the myelin sheath, a white and shiny fatty substance, which is composed by 80% of lipid and 20% of ...
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