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https://www.cochrane.org/CD006056/EMERG_weaning-mechanical-ventilation-using-pressure-support-or-t-tube-spontaneous-breathing-trial
May 27, 2014 · The ability to breathe spontaneously can be assessed with a spontaneous breathing trial using a T-tube (T-piece) or by reducing the applied airway pressure to provide low levels of pressure support (PS) (5 to 10 cm H 2 O). After removal of the endotracheal tube (extubation) the patients are monitored for 48 hours. If over this period ...
https://www.ncbi.nlm.nih.gov/books/NBK482391/
Clinical Significance. Pressure support provides a set amount of pressure during inspiration to support the spontaneously breathing patient. Pressure support eases a patient's ability to overcome the resistance of the endotracheal tube and is often used during weaning because it decreases the effort of breathing.
https://clinicaltrials.gov/ct2/show/NCT00233324
Surfactant Positive Airway Pressure and Pulse Oximetry Trial (SUPPORT) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
https://www.nejm.org/doi/full/10.1056/NEJMoa0911781
We conducted the Surfactant, Positive Pressure, and Oxygenation Randomized Trial (SUPPORT), a controlled, multicenter trial with a 2-by-2 factorial design, to compare two target levels of oxygen ...
http://www.pedsccm.org/FILE-CABINET/pccm/Ferguson-SBT_failure.pdf
Conclusions: A spontaneous breathing trial using pressure support set at higher levels for smaller endotracheal tubes over-estimates readiness for extubation in children and contributes to a higher failed extubation rate. The objective data obtained during an extubation readiness test …
https://jamanetwork.com/journals/jama/fullarticle/2735502
Jun 11, 2019 · This randomized trial compares the effect of 30-minute pressure support vs 2-hour T-piece ventilation strategies in spontaneous breathing trials on rate of successful extubation among patients who had been receiving mechanical ventilation for at least 24 hours.Cited by: 10
https://www.ncbi.nlm.nih.gov/pubmed/31184740
Jun 11, 2019 · Conclusions and Relevance: Among patients receiving mechanical ventilation, a spontaneous breathing trial consisting of 30 minutes of pressure support ventilation, compared with 2 hours of T-piece ventilation, led to significantly higher rates of successful extubation.Cited by: 10
https://litfl.com/spontaneous-breathing-trial/
Sep 14, 2019 · Spontaneous Breathing Trial. by Dr Chris Nickson, last update September 14, 2019. ... Martin Tobin has argued that adding either 5 cm H2O as “physiologic” PEEP or pressure support of 7 cm H2O to overcome the resistance in an endotracheal tube (or both, as is usually done) may actually reduce the “spontaneously” breathing patient’s ...
https://clinicaltrials.gov/ct2/show/NCT01769053
Variable Pressure Support Trial (ViPS) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. ...
https://pulmccm.org/randomized-controlled-trials/trach-collar-beats-pressure-support-trials-for-long-term-ventilator-weaning-rct-jama/
A closely monitored "trach collar" trial may be justified in many more patients than we intuitively believe are ready to wean from the ventilator. Jubran A et al. Effect of pressure support versus unassisted breathing through a tracheostomy collar on weaning duration in patients requiring prolonged mechanical ventilation. A randomized trial.
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