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https://www.cochrane.org/CD009154/MENSTR_luteal-phase-support-assisted-reproduction
Jul 07, 2015 · As a low progesterone level may lower the chance of implantation, the luteal phase needs to be supported. This may involve oral, vaginal or intramuscular progesterone, human chorionic gonadotropin (hCG) (which stimulates progesterone production) or gonadotropin-releasing hormone (GnRH) agonists.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342373/
Progesterone supplementation is universally used and has been shown to be beneficial in supplementation of the luteal phase in IVF. There are multiple options and the most commonly used include intramuscular and vaginal progesterone.Cited by: 3
https://www.yourivfjourney.com/progesterone-the-key-facts-for-ivf-patients/
In short, IVF disrupts your natural progesterone function. So you need lots more of it for proper luteal support, from egg-retrieval day onwards. Progesterone facilitates implantation and can stop a miscarriage in its tracks.
https://ivf-worldwide.com/education/ivf-luteal-support.html
Luteal support In order to achieve pregnancy, a delicate communication between the blastocyst and endometrium is needed over a specific time during the cycle. This period, termed the "Implantation Window" occurs during the luteal phase and is controlled by estrogen (E) and progesterone (P).
https://www.sciencedirect.com/science/article/pii/S0015028209043179
Luteal-phase defect has been reported in both GnRH agonist and GnRH antagonist IVF/ICSI cycles .For this reason, use of medication for luteal-phase support (LPS) has been considered to be mandatory to ensure intact corpus luteum function and avoid any decrease in implantation and pregnancy rates.Cited by: 24
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